Mitch André Garcia Curriculum Vitae

Contact Information
30720 Principio Dr.
Malibu CA, 90265

(510) 684-8092
Public Information
Blog: chemistry-blog.com
CV: chemicalvitae.com/mitch
Education
Graduate Studies
University of California Berkeley
Doctor of Philosophy in Chemistry - 2009
Undergraduate Studies
University of California Riverside
Bachelor of Science in Pure and Applied Chemistry - 2003
Employment
Editor
American Chemical Society
Chemical & Engineering News - 2014 to present
Chief Technology Officer
CytoLumina Technologies Corp. - 2013 to 2014
Postdocdoral Fellow
University of California Los Angeles
Molecular and Medical Pharmacology - 2010 to 2013
Research
University of California Los Angeles, Department of Molecular and Medical Pharmacology, Advisor: Hsian-Rong Tseng, 2010-Present
Postdoctoral training in developing microchips with nanostructures for the capture and isolation of circulating tumor cells. Also, used a novel supramolecular nanoparticle system for the treatment and imaging of cancer cells both in vitro and in vivo.

University of California Berkeley, Department of Chemistry, Advisor: Heino Nitsche, 2005-2009
Graduate student studying nuclear & radiochemistry, materials chemistry, and electronics & circuit design. The thesis focused on three research topics that were distinctly different but broadly centered around developing new methods to perform transactinide gas-phase chemistry. First, the application of a new materials science methodology, Polymer-Assisted Deposition (PAD), to target manufacturing. Second, the construction of a new experimental apparatus to conduct gas-phase chemistry and the design of circuits and electronics for the measurement of alpha-decay energy. Third, a new nuclear reaction for the production of 261Rf, an ideal candidate for gas-phase chemistry due to its relatively-long half life (t1/2 = 69 s).

University of California Berkeley, Department of Chemistry, Advisor: Joseph Cerny, Summer 2002
Undergraduate student studying nuclear chemistry. The project was to develop software that would model the kinematics of Neon-18 decay through the emission of two protons.

University of California Riverside, Department of Chemistry, Advisor: Michael Marsella, 2000 - 2003
Undergraduate student studying organic synthesis and polymer chemistry. The project involved synthesizing dimethyldihydropyrene analogs for use as molecular switches.
Honors, Awards & Press
  1. UCLA's Scholars in Oncologic Molecular Imaging Postdoctoral Fellow -- (2010-present)
    http://www.crump.ucla.edu/somi/index.html
  2. Nature Chemistry -- Smarten up (2010)
    DOI: 10.1038/nchem.601
  3. Chemical & Engineering News Blog -- Blogger In The Press Room (2008)
    http://cenblog.org/2008/08/22/blogger-in-the-press-room/
  4. Chemical & Engineering News Blog -- Chemistry And The Interweb (2008)
    http://cenblog.org/2008/04/07/chemistry-and-the-interweb/
  5. Nature -- The new networking nexus (2008)
    DOI:10.1038/nj7181-1024a
  6. Chemical & Engineering News -- Bloggers Anonymous (2007)
    http://pubs.acs.org/cen/science/85/8505sci2.html/
  7. Chemistry Blog - Editor in Chief (2005-present)
    http://www.chemistry-blog.com/
  8. Chemical Forums - Administrator (2003-present)
    http://www.chemicalforums.com/
  9. UC LEADS Scholar (2001-2003)
    http://www.ucop.edu/ucleads/
Teaching & Mentoring Experience
  1. Guest Lecturer for General Chemistry (Nuclear Chemistry Lecture) at Calstate Fullerton (2011)
  2. Research Mentor for Berkeley Undergraduate Noel N. Chang (2007-2009) (now @ UIUC)
  3. Research Mentor for Berkeley Undergraduate Mazhar N. Ali (2007-2009) (now @ Princeton)
  4. Graduate Student Instructor for Nuclear Chemistry (2006)
  5. Graduate Student Instructor for Organic Chemistry I (2005)
  6. Graduate Student Instructor for Organic Chemistry I (2003)
  7. Undergraduate Student Instructor for Advanced Structural and Synthetic Methods (2003)
  8. Undergraduate Student Instructor for General Chemistry I (2003)
Publications

  1. Jae-Hyun Lee, Kuan-Ju Chen, Seung-Hyun Noh, Mitch Andre Garcia, Hao Wang, Wei-Yu Lin, Heeyeong Jeong, Brian Junoh Kong, David B. Stout, Jinwoo Cheon, Hsian-Rong Tseng "On-Demand Drug Release System for In Vivo Cancer Treatment through Self-Assembled Magnetic Nanoparticles." Angewandte Chemie International Edition 2013 52(16), 4384-4388.
    DOI:10.1002/anie.201207721

  2. Libo Zhao, Yi-Tsung Lu, Fuqiang Li, Kui Wu, Shuang Hou, Juehua Yu, Qinglin Shen, Dongxia Wu, Min Song, Wei-Han OuYang, Zheng Luo, Tom Lee, Xiaohong Fang, Chen Shao, Xun Xu, Mitch A. Garcia, Leland W. K. Chung, Matthew Rettig, Hsian-Rong Tseng, Edwin M. Posadas "High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing." Advanced Materials 2013 25(21), 2897-2902.
    DOI:10.1002/adma.201205237

  3. Qinglin Shen, Li Xu, Libo Zhao, Dongxia Wu, Yunshan Fan, Yiliang Zhou, Wei-Han OuYang, Xiaochun Xu, Zhen Zhang, Min Song, Tom Lee, Mitch A. Garcia, Bin Xiong, Shuang Hou, Hsian-Rong Tseng, Xiaohong Fang "Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates." Angewandte Chemie International Edition 2013 25(16), 2368–2373.
    DOI:10.1002/adma.201300082

  4. Shuang Hou, Libo Zhao, Qinglin Shen, Juehua Yu, Charles Ng, Xiangju Kong, Dongxia Wu, Min Song, Xiaohong Shi, Xiaochun Xu, Wei-Han OuYang, Rongxian He, Xing-Zhong Zhao, Tom Lee, Charles Brunicardi, Mitch André Garcia, Antoni Ribas, Roger S. Lo, Hsian-Rong Tseng "Polymer Nanofiber-Embedded Microchips for Detection, Isolation, and Molecular Analysis of Single Circulating Melanoma Cells." Angewandte Chemie International Edition 2013 52(12), 3379–3383.
    DOI:10.1002/anie.201208452

  5. Shuang Hou, Haichao Zhao, Libo Zhao, Qinglin Shen, Kevin S. Wei, Daniel Y. Suh, Aiko Nakao, Mitch A. Garcia, Min Song, Tom Lee, Bin Xiong, Shyh-Chyang Luo, Hsian-Rong Tseng, Hsiao-hua Yu "Capture and Stimulated Release of Circulating Tumor Cells on Polymer-Grafted Silicon Nanostructures." Advanced Materials 2013 25(11), 1547–1551.
    DOI:10.1002/adma.201203185

  6. Kuan-Ju Chen, Li Tang, Mitch André Garcia, Hao Wang, Hua Lu, Wei-Yu Lin, Shuang Hou, Qian Yin, Clifton K.-F. Shen, Jianjun Cheng, Hsian-Rong Tseng "The therapeutic efficacy of camptothecin-encapsulated supramolecular nanoparticles." Biomaterials 2012 33(4), 1162-1169.
    DOI:10.1016/j.biomaterials.2011.10.044

  7. Hao Wang, Kan Liu, Kuan-Ju Chen, Yujie Lu, Shutao Wang, Wei-Yu Lin, Feng Guo, Ken-ichiro Kamei, Yi-Chun Chen, Minori Ohashi, Mingwei Wang, Mitch André Garcia, Xing-Zhong Zhao, Clifton K.-F. Shen, Hsian-Rong Tseng "A Rapid Pathway Toward a Superb Gene Delivery System: Programming Structural and Functional Diversity into a Supramolecular Nanoparticle Library." ACS Nano 2010 4(10), 6235-6243.
    DOI:10.1021/nn101908e

  8. Mazhar N Ali, Mitch A Garcia, T Parsons-Moss, Heino Nitsche "Polymer-assisted deposition of homogeneous metal oxide films to produce nuclear targets" Nature Protocols 2010 5, 1440-1446.
    DOI:10.1038/nprot.2010.105

  9. Kuan-Ju Chen, Stephanie M. Wolahan, Hao Wang, Chao-Hsiung Hsu, Hsing-Wei Chang, Armando Durazo, Lian-Pin Hwang, Mitch A. Garcia, Ziyue K. Jiang, Lily Wu, Yung-Ya Lin, Hsian-Rong Tseng "A small MRI contrast agent library of gadolinium(III)-encapsulated supramolecular nanoparticles for improved relaxivity and sensitivity" Biomaterials 2010 32(8), 2160-2165.
    DOI:10.1016/j.biomaterials.2010.11.043

  10. Hao Wang, Kan Liu, Kuan-Ju Chen, Yujie Lu, Shutao Wang, Wei-Yu Lin, Feng Guo, Ken-ichiro Kamei, Yi-Chun Chen, Minori Ohashi, Mingwei Wang, Mitch André Garcia, Xing-Zhong Zhao, Clifton K.-F. Shen, Hsian-Rong Tseng "A Rapid Pathway Toward a Superb Gene Delivery System: Programming Structural and Functional Diversity into a Supramolecular Nanoparticle Library" ACS Nano 2010 4, 6235-6243. (cover)
    DOI:10.1021/nn101908e

  11. Garcia, M.A. "The race for rutherfordium" Nature Chemistry 2010 2, 66.
    DOI:10.1038/nchem.499

  12. Düllmann, Ch. E.; Gregorich, K. E.; Pang, G. K.; Dragojevic, I.; Eichler, Robert; Folden III, C.M.; Garcia, M. A.; Gates, J. M.; Hoffman, D.C.; Nelson, S. L.; Sudowe, R; Nitsche, H "Gas chemical investigation of hafnium and zirconium complexes with hexafluoroacetylacetone using preseparated short-lived radioisotopes" Radiochimica Acta 2009 97(8), 403-418.
    DOI:10.1524/ract.2009.1630

  13. C. M. Folden III, I. Dragojevic, Ch. E. Düllmann, R. Eichler, M. A. Garcia, J. M. Gates, S. L. Nelson, R. Sudowe, K. E. Gregorich, D. C. Hoffman, H. Nitsche "Measurement of the 208Pb(52Cr,n)259Sg excitation function" Phys. Rev. C 2009 79, 027602.
    DOI:10.1103/PhysRevC.79.027602

  14. Garcia, M.A.; Ali, M.N.; Chang, N.N.; Parsons-Moss, T; Ashby, P.D.; Gates, J.M.; Stavsetra, L.; Gregorich, K.E.; Nitsche, H. "Heavy-ion irradiation of thulium(III) oxide targets prepared by polymer-assisted deposition" Nucl. Instrum. Meth. A 2008 592, 483-485.
    DOI:10.1016/j.nima.2008.04.077

  15. Garcia, M.A.; Ali, M.N.; Parsons-Moss, T; Ashby, P.D.; Nitsche, H. "Metal oxide films produced by polymer-assisted deposition (PAD) for nuclear science applications" Thin Solid Films 2008 516, 6261-6265.
    DOI:10.1016/j.tsf.2007.11.127
  16. Gates, J.M.; Garcia, M.A.; Gregorich, K.E.; Dullmann, Ch.E.; Dragojevic, I.; Dvorak, J.; Eichler, R.; Folden III, C.M.; Loveland, W.; Nelson, S.L.; Pang, G.K.; Stavsetra, L; Sudowe, R.; Turler, A.; Nitsche, H. "Synthesis of rutherfordium isotopes in the 238U(26Mg, xn)264-xRf reaction and study of their decay properties" Phys. Rev. C 2008 77, 034603-034609.
    DOI:10.1103/PhysRevC.77.034603
  17. Dragojevic, I.; Gregorich, K.E.; Düllmann, Ch. E.; Garcia, M.A.; Gates, J.M.; Nelson, S.L.; Stavsetra, L.; Sudowe, R.; Nitsche, H. "Influence of projectile neutron number in the 208Pb(48Ti, n)255Rf and 208Pb(50Ti, n)257Rf reactions" Phys. Rev. C 2008 78, 024605.
    DOI:10.1103/PhysRevC.78.024605
  18. Nelson, S.L.; Folden III, C.M.; Gregorich, K.E.; Dragojevic, I.; Düllmann, Ch. E.; Eichler, R.; Garcia, M.A.; Gates, J.M.; Sudowe, R.; Nitsche, H. "Comparison of complementary reactions for the production of 261,262Bh" Phys. Rev. C 2008 78, 024606.
    DOI:10.1103/PhysRevC.78.024606
  19. Nelson, S.L.; Gregorich, K.E.; Dragojevic, I; Garcia, M.A.; Sudowe, R.; Nitsche, H. "Lightest Isotope of Bh Produced via the 209Bi(52Cr,n)260Bh Reaction" Phys. Rev. Lett. 2008 100, 022501-4.
    DOI:10.1103/PhysRevLett.100.022501
Conference Presentations

  1. Chen, K.-J.; Garcia, M.A.; Wang, H.; Tseng, H.-R. "Drug(s)-Encapsulate Supramolecular Nanoparticles for Cancer Treatment" 2011 Nanomedicine and Drug Delivery, Los Angeles, USA, March 4-5, 2011. (poster)
  2. Garcia, M.A.; Ali, M.N.; Chang, N.N.; Parsons-Moss, T; Ashby, P.D.; Nitsche, H. "Metal Oxide Targets Produced by the Polymer-Assisted Deposition Method" 24th World Conference of the International Nuclear Target Development Society, Caen, France, September 15-19, 2008. (oral)
  3. Garcia, M.A.; Ali, M.N.; Chang, N.N.; Parsons-Moss, T; Ashby, P.D.; Nitsche, H. "Using Polymer-Assisted Deposition for Nuclear Science Applications" 236th ACS National Meeting & Exposition, Philadelphia, PA, August 17-21, 2008. (oral)
  4. Garcia, M.A.; Ali, M.N.; Chang, N.N.; Nitsche, H. "Development of chemical forums, blogs, wikis, RSS feeds, crowdsourcing, and social bookmarking websites for chemistry" 235th ACS National Meeting & Exposition, New Orleans, LA, April 6-10, 2008. (oral)
  5. Garcia, M.A.; Ali, M.N.; Chang, N.N.; Parsons-Moss, T; Ashby, P.D.; Nitsche, H. "Metal Oxide Films Produced by Polymer-Assisted Deposition (PAD) for Nuclear Science Applications " 2007 Molecular Foundry User Meeting, Berkeley, California 2007. (poster)